Contribution of social factors to opiate-induced activation in the mouse.
نویسندگان
چکیده
Adult male Swiss-Webster mice of varying group size (single, or in groups of 2, 3, or 4) were injected with vehicle, or 2.5 or .50mg/lcg of morphine sulfate. In comparison with vehicle, morphineinjected mice showed heightened behavioral activity consisting mainly of stereotyped forward locomotion. This motor response was disproportionately enhanced by the presence of conspecifics. This suggests that morphine-induced activation of grouped animals reflects both jndividual activation responses and the further influence of social factors.
منابع مشابه
P-70: The Effect of Hydrostatic Pressure on Parthenogenetic Activation of Mouse Oocytes Derived from In vitro Grown Ovarian Follicles
Background: Parthenogenesis is the production of an embryo from a female gamete in the absence of any contribution from a male gamete, with or without the eventual development into an adult. In vivo, mammalian parthenogenesis is a rare event. Parthenogenesis can be efficiently induced in vitro with a variety of mechanical, chemical, and electrical stimuli in several species. Hydrostatic pressur...
متن کاملInvolvement of central opiate receptors in modulation of centrally administered oxytocin-induced antinociception
Objective(s): Oxytocin is involved in modulation of many brain-mediated functions. In the present study, we investigated the central effects of oxytocin and its receptor antagonist, atosiban on inflammatory pain. The contribution of opiate receptors was explored using non-selective and selective antagonists. Materials and Methods: The fourth ventricle of the brain of anesthetized rats was impla...
متن کاملDetermining Factors Affecting Fire Risk in a Hospital in Qazvin, Iran
Background: Hospitals are highly vulnerable to fire because of the presence of vulnerable people (patients, medical staff, and visitors), expensive equipment, and the ignorance and low-risk perception of occupants. Injuries caused by fire can result in life and financial losses and can disrupt the performance of a hospital. Fire risk assessment is an effective way to assess vulnerability, capac...
متن کاملInhibitory effects of Cheonggukjang extracts on radiation-induced micronucleus formation and inflammasome activation
Background: People are exposed to more radiation than before with the application of radiation technology. Radiation is known to induce damage to cell structure, DNA, chromosomes and nucleus. In this study, we showed that CGJ extract can inhibit radiation-induced chromosomal damage in vivo and NLRP7 inflammasome activation in vitro, suggesting that the compound from CGJ can Be considered as a t...
متن کاملEffects of Yacon on Colonic IFN-γ and Goblet Cells of 2,4,6-Trinitrobenzene Sulfonic Acid-Induced Colitis Mouse Model
Background: IBD is a chronic inflammatory condition associated with damage to the intestinal mucosal barrier. Supplementation of yacon tubers has been known to give positive effect in intestinal health. Therefore, we conducted the study to investigate the effect of yacon tuber powder on Th1 activation pathway by evaluating IFN-γ levels and the number of goblet cells in the colon of colitis mous...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Neuropharmacology
دوره 20 4 شماره
صفحات -
تاریخ انتشار 1981